A PLOS Medicine study published September 17 analyzed wrist-accelerometer data from 95,559 UK Biobank participants, then followed them for a median of about 8.9 years against more than 1,000 health outcomes. Greater REM sleep was associated with lower risk of 83 conditions (including heart failure, dementia, and Parkinson’s), while more deep sleep linked to lower risk of seven conditions such as type 2 diabetes and major depression. Sleeping under five hours lined up with elevated risk across dozens of diagnoses; the lowest risk for many conditions clustered in a 6–8 hour window.

Medical News Today’s September 18 write-up stresses the usual caveats: this is observational, and reverse causation can muddy some links (depression often disrupts sleep first). The practical weekend takeaway from clinicians they interviewed is boring on purpose: keep a consistent wake time even after a late night, get morning daylight soon after rising, cool and dark the bedroom, and treat wearables as mirrors rather than grades. Protecting sleep stages beats chasing a perfect score.

Zach Cregger’s Resident Evil reboot opened Friday across roughly 3,500 North American theaters and is the clear theatrical story of the weekend. Thursday previews alone took about $8.8–9 million, already a franchise record for a single day, and Friday domestic estimates around $24 million have trackers talking about a $50 million-plus opening weekend, well above the series’ prior domestic debuts. The film carries a roughly $75 million production budget and, unusually for this franchise, arrived with strong reviews (Rotten Tomatoes was near 96% in pre-opening coverage).

Holdovers and alternatives: Practical Magic 2 and Spider-Man: Brand New Day continue, with Aardman’s Shaun the Sheep: The Beast of Mossy Bottom also in wide release. If you want one big-screen plan before Monday’s box-office autopsy, this is the one the industry is watching.

Two easy, free-leaning stops stack nicely this afternoon and evening. Denver BAZAAR returns to historic Larimer Square every third Saturday through October; today’s market runs 3–8 p.m. with 30-plus local vendors and makers. It’s free, dog-friendly, and all-ages: a low-stakes LoDo wander before dinner.

From 5–10 p.m., Chamberlin Observatory and Observatory Park host International Observe the Moon Night. Denver Astronomical Society volunteers will have telescopes on the south lawn; weather permitting, the historic 20-inch Alvan Clark–Saegmuller refractor opens for lunar views (limited ticketed access inside the observatory). Bring a jacket for cooling evening air, and if you just bought a telescope, DAS folks will help you set it up before dark. Participating partners include DarkSky Colorado, Denver Public Library’s Bookmobile, and several Front Range science orgs. Address: 2930 E. Warren Ave.